Ion Channel Assays

ENaC Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

ENaC - QPatch

enac assay

Figure 1: Time-course experiment (current vs time) in which cumulative concentrations of Amiloride were applied.

ENaC - Manual Patch Clamp

enac assay

Figure 2: Concentration-dependent effect of Amiloride on normalised (I/Imax) currents. Calculated IC50 = 0.7 µM.

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