GPCR assays

AdoR Assays

Species: Human

Subtypes: A1, A2A, A2B, A3

Assay Formats: Radioligand binding (A1, A2A, A2B), Cell-based assay (A1, A2A, A2B, A3)

Services: HTS, single concentration / dose response studies, selectivity profiling

 

ADORA1 - Ligand binding assay

AdoR A1 binding assay

Figure 1: Dose response curve for ligand in an AdoR A1 radioligand binding assay. Approximate IC50 438nM.

 

ADORA2a - Ligand binding assay

AdoR A2A binding assay

Figure 2: Dose response curve for ligand in an AdoR A2a radioligand binding assay. Approximate IC50 5.73μM.

 

ADORA1 - Cell-based assay

AdoR A1 binding assay

Figure 3: Dose response curve for DPDX in an AdoR A1 cell-based assay. Approximate IC50 65 nM.

 

ADORA2a - Cell-based assay

AdoR A2a cell based assay

Figure 4: Dose response curve for 8-(3-chlorostyryl) caffine in an AdoR A2a cell-based assay. Approximate IC50 339 nM.


Back to Overview
Request a Screening Quote