Calcium Channel Screening Services
Voltage-gated calcium channels (VGCC) are found in excitable cells such as muscle and neurons and consist of an α1 ion-conducting pore which forms a complex with associated subunits (α2δ, β1-4, γ). There are various voltage-gated calcium channel α1 subtypes, namely the L-type (Cav1.1, 1.2, 1.3, 1.4), P/Q-type (Cav2.1), N-type (Cav2.2), R-type (Cav2.3) and T-type (Cav3.1, 3.2. 3.3) channels.
SB Drug Discovery has developed stable calcium channel cell lines and validated screening & profiling assays for HTS, lead optimization studies and selectivity profiling. Our assays have been validated by experienced in-house electrophysiologists using rigorously optimized SOPs to ensure data of the highest quality and consistency.
To discuss your next ion channel project or to receive a quote, visit our contact page or call +44 141 587 6100.