Cav1.2 assay

Cav1.2 Screening Assays

Species: Human

Subunits / Accessory Proteins: β2, α2δ1

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Cav1.2 - Manual Patch Clamp

Cav1.2 assay

Figure 1: Concentration-dependent effects of FPL-61476 on ICa currents (pA) obtained from HEK-293 cells stably transfected with human Cav 1.2 channels. Calculated EC50 value 4 µM.

Cav1.2 - Manual Patch Clamp

Cav1.2 assay

Figure 2: Concentration-dependent effect of nifedipine on ICa currents (pA) obtained from HEK-293 cells stably transfected with human Cav 1.2 channels. Calculated IC50 value 49 nM.


Back to Family
Request a Screening Quote