Cav1.2 assay

Cav2.1 Screening Assays

Species: Human

Subunits / Accessory Proteins: β3, α2δ1

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, Automated Electrophysiology

Services: HTS, single concentration / dose response studies, selectivity profiling

Cav2.1 - QPatch

Cav2.1 assay

Figure 1: Effect of mibefradil on Cav2.1 current. Absolute currents (pA) shown in the presence and absence of increasing concentrations of mibefradil.

Cav2.1 - QPatch

Cav2.1 assay

Figure 2: Concentration-dependent effect of mibefradil on ICa currents (nA) obtained from HEK-293 cells stably transfected with human Cav2.1 channels.

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