TRPA1 assay

Dog TRPA1 Screening Assays

Species: Dog

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: FLIPR, Manual Patch Clamp

Services: HTS, single concentration / dose response studies, selectivity profiling

Dog TRPA1 - Fluorescence Assay

TRPA1 assayFigure 1: EC50 plot showing increasing concentrations of agonist AITC in a FLIPR calcium assay (approximate EC50 value 14 μM).

Dog TRPA1 - Fluorescence Assay

TRPA1 assayFigure 2: IC50 plot showing increasing concentrations of antagonist Ruthenium Red in a FLIPR calcium assay (approximate IC50 value 7.6 μM).

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