GABAA Receptor Screening Services
GABAA receptors are ligand-gated ion channels which respond to the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). There are many subunit isoforms for the GABAA receptor of which 5 are required to make up a functional channel (usually 2 α's, 2 β's and a single γ). Subunit composition plays a role in agonist affinity and varies depending on the region of the brain.
SB Drug Discovery offers a comprehensive panel of GABAA assays for HTS, lead optimization studies and selectivity profiling. Our assays have been validated by experienced in-house electrophysiologists using rigorously optimized SOPs to ensure data of the highest quality and consistency.
To discuss your next ion channel project or to receive a quote, visit our contact page or call +44 141 587 6100.
GABAA receptor assays
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