GPCR assays

Histamine Receptor Assays

Species: Human

Subtypes: H1, H2 (others available on request)

Assay Formats: Cell-based assay (H1, H2)

Services: HTS, single concentration / dose response studies, selectivity profiling

 

Histamine H1 - Cell-based assay

Histamine H1 assay

Figure 1: Dose response curve for agonist Histamine in an H1 cell-based assay. Approximate EC50 29.9 nM.

 

Histamine H1 - Cell-based assay

Histamine H1 assay

Figure 2: Dose response curve for antagonist Aripiprazole in an H1 cell-based assay. Approximate IC50 2.6 μM.

 

Histamine H2 - Cell-based assay

Histamine H2 assay

Figure 3: Dose response curve for agonist Histamine in an H2 cell-based assay. Approximate EC50 2.9 μM.

 

Histamine H2 - Cell-based assay

Histamine H2 assay

Figure 4: Dose response curve for antagonist Ranitidine in an H2 cell-based assay. Approximate IC50 8 μM.


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