GPCR assays

Opioid Receptor Assays

Species: Human

Subtypes: δ-opioid, κ-opioid, μ-opioid (others available on request)

Assay Formats: Cell-based assay (δ-opioid, κ-opioid, μ-opioid)

Services: HTS, single concentration / dose response studies, selectivity profiling

 

δ-Opioid - Cell-based assay

opioid receptor assay

Figure 1: Dose response curve for agonist DPDPE in a δ-opioid cell-based assay. Approximate EC50 57 nM.

 

δ-Opioid - Cell-based assay

opioid receptor assay

Figure 2: Dose response curve for antagonist Naltridole in a δ-opioid cell-based assay. Approximate IC50 1.5 nM.

 

μ-Opioid - Cell-based assay

opioid receptor assay

Figure 3: Dose response curve for agonist DAMGO in a μ-opioid cell-based assay. Approximate EC50 231 nM.

 

μ-Opioid - Cell-based assay

opioid receptor assay

Figure 4: Dose response curve for antagonist CTOP in a μ-opioid cell-based assay. Approximate IC50 29.9 nM.


Back to Overview
Request a Screening Quote