TRP Channels

Guinea Pig TRPA1 Screening Assays

Species: Guinea Pig

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp

Services: HTS, single concentration / dose response studies, selectivity profiling

Guinea Pig TRPA1 - Fluorescence Assay

TRPA1 assay

Figure 1: Dose response curve of agonist AITC against guinea pig TRPA1 using calcium sensitive dye assay.  EC50 value 6.03µM.

Guinea Pig TRPA1 - Fluorescence Assay

TRPA1 assay

Figure 2: Dose response curve of antagonist ruthenium red against guinea pig TRPA1 using calcium sensitive dye assay.  IC50 value  95.8µM.


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