Potassium Channel Assays

KCa4.1 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

KCa4.1 - QPatch

KCa4.1 assay

Figure 1: Concentration-response curve of loxapine on KCa4.1 expressing cells. Calculated EC50 was 4 µM.

KCa4.1 - QPatch

KCa4.1 assay

Figure 2: Concentration-dependent effects of quinidine against KCa4.1 expressing cells. Calculated IC50 2.57 µM.

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