Potassium Channel Assays

Kir2.4 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Kir2.4 - Manual Patch Clamp

Kir2.4 assay

Figure 1: Superimposed current-voltage traces from Kir2.4 expressing cells showing a concentration-dependent block induced by BaCl2.

Kir2.4 - Manual Patch Clamp

Kir2.4 assay

Figure 2: Concentration-dependent effect of BaCl2 on normalised currents (I/Imax) obtained from cells stably expressing Kir2.4 channels. Calculated IC50 1 µM.


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