Potassium Channel Assays

Kv1.3 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Kv1.3 - QPatch

Kv1.3 assay

Figure 1: Time-course showing effect of Kaliotoxin against Kv1.3 currents obtained from cells expressing Kv1.3.

Kv1.3 - QPatch

Kv1.3 assay

Figure 2: Concentration-response curve for Kaliotoxin against Kv1.3  currents. Extrapolated IC50 approximately 70 pM.


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