Potassium Channel Assays

Kv2.2 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Kv2.2 - Manual Patch Clamp

kv2.2 assay

Figure 1: Current-Voltage relationships of IKv. The average IK (G/Gmax) is shown V50=34 mV.

Kv2.2 - QPatch

kv2.2 assay

Figure 2: Concentration-dependent effects of TEA and Quinine on IKv currents (pA). Calculated IC50 values were 15.6 and 0.11 mM respectively.

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