Potassium Channel Assays

Kv3.1 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Kv3.1 - Manual Patch Clamp

kv3.1 assay

Figure 1: Concentration-dependent effect of 4-AP on peak currents obtained from HEK-293 cells stably transfected with Kv3.1.

Kv3.1 - QPatch

kv3.1 assay

Figure 2: Concentration-dependent effect of antagonist TEA on cells stably transfected with Kv3.1.  Calculated IC50 1 μM.


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