Kv3.1 Screening Assays
Species:Â Human
Subunits / Accessory Proteins:Â N/A
Cell Type:Â HEK-293
Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch
Services: HTS, single concentration / dose response studies, selectivity profiling
Kv3.1 - Manual Patch Clamp

Figure 1: Concentration-dependent effect of 4-AP on peak currents obtained from HEK-293 cells stably transfected with Kv3.1.
Kv3.1 - QPatch

Figure 2: Concentration-dependent effect of antagonist TEA on cells stably transfected with Kv3.1. Calculated IC50 1 μM.