Potassium Channel Assays

Kv4.3/KChIP2 Screening Assays

Species: Human

Subunits / Accessory Proteins: KChIP2

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Kv4.3/KChIP2 - Manual Patch Clamp

Kv4.3 assay

Figure 1: Current-voltage relationship of HEK-293 cells stably transfected with Kv4.3+KChIP. Calculated activation V½ was approximately 16 mV.

Kv4.3/KChIP2 - Manual Patch Clamp

Kv4.3 assay

Figure 2: Concentration-dependent effect of 4-AP on IKv4.3+KChIP currents. Calculated IC50 value approximately 12 mM.


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