Potassium Channel Assays

Kv7.1 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Kv7.1 - QPatch

KCNQ1 assay

Figure 1:  Representative superimposed current-voltage traces from Kv7.1 cell line.

Kv7.1 - QPatch

KCNQ1 assay

Figure 2: Concentration dependent effect of antagonist XE-991 on cells stably transfected with Kv7.1 channels.  Calculated IC50 0.9 μM.

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