Potassium Channel Assays

Kv7.2 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

Kv7.2 - QPatch

kv7.2 assay

Figure 1: Concentration-dependent inhibitory effects of XE-991 on normalised currents (I/Imax) obtained from HEK-293 cells stably expressing Kv7.2 channels. Calculated IC50 0.33 μM .

Kv7.2 - QPatch

kv7.2 assay

Figure 2: Concentration-dependent inhibitory effects of TEA on normalised currents (I/Imax) obtained from HEK-293 cells stably expressing Kv7.2 channels. Calculated IC50 value 152 μM.


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