Protease assays

Matrix Metalloproteases

Species: Human

Subtypes: MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP12, MMP13, MMP14, MMP19, MMP20

Assay Format: Fluorescence

Services: HTS, IC50 determination, selectivity profiling

MMP-1

MMP1 assay

Figure 1: Concentration-dependent effect of NNGH on MMP-1 activity.

MMP-2

MMP2 assay

Figure 2: Concentration-dependent effect of NNGH on MMP-2 activity.

MMP-3

MMP3 assay

Figure 3: Concentration-dependent effect of NNGH on MMP-3 activity.

MMP-7

MMP7 assay

Figure 4: Concentration-dependent effect of NNGH on MMP-7 activity.

MMP-8

MMP8 assay

Figure 5: Concentration-dependent effect of NNGH on MMP-8 activity.

MMP-9

MMP9 assay

Figure 6: Concentration-dependent effect of NNGH on MMP-9 activity.

MMP-10

MMP10 assay

Figure 7: Concentration-dependent effect of NNGH on MMP-10 activity.

MMP-12

MMP12 assay

Figure 8: Concentration-dependent effect of NNGH on MMP-12 activity.

MMP-13

MMP13 assay

Figure 9: Concentration-dependent effect of NNGH on MMP-13 activity.

MMP-14

MMP14 assay

Figure 10: Concentration-dependent effect of NNGH on MMP-14 activity.

MMP-19

MMP19 assay

Figure 11: Concentration-dependent effect of NNGH on MMP-19 activity.

MMP-20

MMP20 assay

Figure 12: Concentration-dependent effect of NNGH on MMP-20 activity.


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