P2X Channels

Mouse P2X7 Screening Assays

Species: Mouse

Subunits / Accessory Proteins: N/A

Cell Type: HEK293

Assay Platforms: Fluorescence, Manual Patch Clamp

Services: HTS, single concentration / dose response studies, selectivity profiling

Mouse P2X7 - Manual Patch Clamp

P2X7 assay

Figure 1: Concentration-dependent effect of BZ-ATP on cells stably expressing mouse P2X7 channels. Calculated EC50 approximately 63 µM.

Mouse P2X7 - Manual Patch Clamp

P2X7 assay

Figure 2: Concentration-dependent effect of KN-62 on cells stably expressing mouse P2X7 channels. Calculated IC50 approximately 9 nM .


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