TRPA1 assay

Mouse TRPA1 Screening Assays

Species: Mouse

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: FLIPR, Manual Patch Clamp, Automated Patch Clamp

Services: HTS, single concentration / dose response studies, selectivity profiling

Mouse TRPA1 - Manual Patch Clamp

TRPA1 assayFigure 1: Representative example of time course during application of cumulative concentrations of AITC (0.1-100 µM) and Ruthenium red (100 mM).

Mouse TRPA1 - Manual Patch Clamp

TRPA1 assayFigure 2: EC50 plot for AITC with the maximum outward value at the top concentration of AITC used as 1.0 and the baseline current in the absence of agonist used as 0.0.

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