Nicotinic Receptors

Nicotinic Receptors

Nicotinic Receptors

Nicotinic acetylcholine receptors, or nAChRs, are receptors that respond to the neurotransmitter acetylcholine. These receptors belong to a superfamily of ligand-gated ion channels and are known to play key roles in synaptic transmission throughout the central nervous system. Many subtypes of nAChR are known to exist, composed of different combinations of subunits which in combination with their broad distribution throughout the central and peripheral nervous systems, enable them to play multiple, varied roles.

SB Drug Discovery offers nAChR assays for HTS, lead optimization studies and selectivity profiling. Our assays have been validated by experienced in-house electrophysiologists using rigorously optimized SOPs to ensure data of the highest quality and consistency.

To discuss your next ion channel project or to receive a quote, visit our contact page or call +44 141 587 6100.

Nicotinic Receptors

Channel Species Fluorescense Assay Electrophysiology Assay
nAChR α3β4 Human Green Dot Green Dot
nAChR α4β2 Human Green Dot Green Dot
nAChR α7 Human Green Dot Green Dot