NMDA (NR1/2A) Screening Assays
Species: Human
Subunits / Accessory Proteins: N/A
Cell Type: HEK293
Assay Platforms: Fluorescence, Manual Patch Clamp, Automated Electrophysiology
Services: HTS, single concentration / dose response studies, selectivity profiling
NMDA NR1/2A - Fluorescence Assay

Figure 1: Concentration dependent effect of agonist Glutamate (co-applied with Glycine). Calculated EC50 value approximately 546 nM.
NMDA NR1/2A - Fluorescence Assay

Figure 2: Concentration dependent effect of antagonist MK-801. Calculated IC50 value approximately 96 nM.