Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK293

Assay Platforms: Fluorescence, Manual Patch Clamp, Automated Electrophysiology

Services: HTS, single concentration / dose response studies, selectivity profiling

NMDA NR1/2A - Fluorescence Assay

Figure 1:  Concentration dependent effect of agonist Glutamate (co-applied with Glycine). Calculated EC₅₀ value approximately 546 nM.

NMDA NR1/2A - Fluorescence Assay

Figure 2: Concentration dependent effect of antagonist MK-801. Calculated IC₅₀ value approximately 96 nM.