Nuclear Receptors

Estrogen Receptor Assays

Species: Human

Subtypes: ER-α, ER-β

Assay Format: Radioligand binding

Services: HTS, single concentration / dose response studies, selectivity profiling

 

ER-α - Ligand binding assay

Estrogen receptor assay

Figure 1: Dose response curve for ligand diethylstilbestrol. IC50 value 140 nM.

 

ER-β - Ligand binding assay

Estrogen receptor assay

Figure 2: Dose response curve for ligand diethylstilbestrol. IC50 value 31.4 nM.


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