Nuclear Receptors

Retinoic Acid Receptor (RAR) Assays

Species: Human

Subtypes: RAR-α, RAR-β, RAR-γ

Assay Format: Radioligand binding

Services: HTS, single concentration / dose response studies, selectivity profiling

 

RAR-α - Ligand binding assay

Retinoic acid receptor assay

Figure 1: Dose response curve for the ligand retinoic acid. IC50 value 19.2 nM.

 

RAR-β - Ligand binding assay

Retinoic acid receptor assay

Figure 1: Dose response curve for the ligand retinoic acid. IC50 value 24.8 nM.

 

RAR-γ - Ligand binding assay

Retinoic acid receptor assay

Figure 1: Dose response curve for the ligand retinoic acid. IC50 value 65.6 nM.


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