P2X Channels

P2X3 Screening Assays

Species:Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK

Assay Platforms: Fluorescence

Services: HTS, single concentration / dose response studies, selectivity profiling

P2X3 - Fluorescence Assay

P2X3 assay

Figure 1: Concentration-dependent effects of α,β-MeATP on HEK cells stably transfected with human P2X3. Calculated EC50 value approximately 1.51 μM.

P2X3 - Fluorescence Assay

P2X3 assay

Figure 2:  Concentration-dependent effects of RO3 on HEK cells stably transfected with human P2X3 channels. Calculated IC50 value approximately 67.8 nM.


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