P2X Channels

P2X5 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK293

Assay Platforms: Fluorescence, Manual Patch Clamp

Services: HTS, single concentration / dose response studies, selectivity profiling

P2X5 - Manual Patch Clamp

P2X5 assay

Figure 1: Concentration-dependent effects of ATP obtained from HEK-293 cells stably transfected with P2X5 channels. Calculated EC50 value approximately 0.3 µM.

P2X5 - Manual Patch Clamp

P2X5 assay

Figure 2: Inhibitory effect of antagonist Suramin (30 µM) on the ATP-induced activation obtained from HEK-293 cells stably expressing P2X5 channels. 


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