P2X Channels

P2X7 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK293

Assay Platforms: Fluorescence, Manual Patch Clamp

Services: HTS, single concentration / dose response studies, selectivity profiling

P2X7 - Manual Patch Clamp

P2X7 assay

Figure 1: Concentration-dependent effect of agonist Bz-ATP on cells stably expressing P2X7 channels. Calculated EC50 value 13 µM.

P2X7 - Manual Patch Clamp

P2X7 assay

Figure 2: Effect of  antagonist KN-62 on the BZ-ATP-activated current obtained from cells stably expressing P2X7 channels. 


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