PDE Assays

PDE Enzymes

SB's recombinant PDEs are partially purified enzymes cloned from cDNA libraries and expressed in S. frugiperda insect cells using a baculovirus expression system.

Enzymes are available for purchase in 10U vials where 1 unit is defined as the amount of PDE enzyme that will convert 1picomole cAMP or cGMP to AMP or GMP respectively per min at pH7.5 at 30°C.

PDE family-specific antibodies are also available, contact SB for further details.

PDE Enzymes

PDE Isoforms
PDE 1 1CAT, 1A3, 1B, 1C
PDE 2 2CAT, 2A3
PDE 3 3CAT, 3A, 3B
PDE 4 4ACAT, 4A1, 4A4, 4A10, 4BCAT, 4B1, 4B2, 4B3, 4C2, 4DCAT, 4D1, 4D2, 4D3, 4D4, 4D5, 4D7
PDE 5 5CAT, 5A1, 5A2, 5A3
PDE 6 6AB, 6C
PDE 7 7CAT, 7A, 7B
PDE 8 8CAT, 8A1, 8B
PDE 9 9CAT, 9A1, 9A2
PDE 10 10CAT, 10A1, 10A2
PDE 11 11CAT, 11A1

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