PDE Assays

PDE10 assays

Species: Human, Mouse, Rat

Human Isoforms Available: 10CAT, 10A1, 10A2

Source: Recombinant, expressed in insect cells

Assay Formats: IMAP, Radiometric

Services: HTS, IC50 determination, selectivity profiling

PDE10 isoforms

PDE10 assay

Figure 1: Inhibition profile of papaverine against PDE10 isoforms in a radiometric PDE assay.

Mouse PDE10A2

PDE10 assay

Figure 2: Inhibition profile of papaverine against mouse PDE10A2 in a radiometric PDE assay.

Rat PDE10A2

PDE10 assay

Figure 3: Inhibition profile of papaverine against rat PDE10A2 in a radiometric PDE assay.

Monkey PDE10A2

PDE10 assay

Figure 4: Inhibition profile of papaverine against monkey PDE10A2 in a radiometric PDE assay.


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