PDE Assays

PDE3 assays

Species: Human, Mouse, Rat, Guinea Pig, Ferret, Dog, Monkey

Human Isoforms Available: 3CAT, 3A, 3B

Source: Recombinant, expressed in insect cells

Assay Formats: IMAP, Radiometric

Services: HTS, IC50 determination, selectivity profiling

PDE3 isoforms

PDE3 assay

Figure 1: Inhibition profile of cilostazol against PDE3 isoforms in a radiometric PDE assay.

Mouse PDE3

PDE3 assay

Figure 2: Inhibition profile of cilostazol against mouse PDE3 in a radiometric PDE assay.

Rat PDE3

PDE3 assay

Figure 3: Inhibition profile of cilostazol against rat PDE3 in a radiometric PDE assay.

Guinea Pig PDE3

PDE3 assay

Figure 4: Inhibition profile of cilostazol against guinea pig PDE3 in a radiometric PDE assay.

Ferret PDE3

PDE3 assay

Figure 5: Inhibition profile of cilostazol against ferret PDE3 in a radiometric PDE assay.

Dog PDE3

PDE3 assay

Figure 6: Inhibition profile of cilostazol against dog PDE3 in a radiometric PDE assay.

Monkey PDE3

PDE3 assay

Figure 7: Inhibition profile of cilostazol against monkey PDE3 in a radiometric PDE assay.


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