TRP Channels

Rat TRPV1 Screening Assays

Species: Rat

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp

Services: HTS, single concentration / dose response studies, selectivity profiling

Rat TRPV1 - Manual Patch Clamp

trpv1 assay

Figure 1: Normalised concentration-dependent effect of capsaicin on cells stably expressing rat TRPV1 channels. Calculated EC50 approximately 0.3 μM.

Rat TRPV1 - Manual Patch Clamp

trpv1 assay

Figure 2: Normalised concentration response of the effect of Capsazepine against the Capsaicin activated rat TRPV1 current. Calculated IC50 approximately 20 nM .

 

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