Sodium Channel Screening Services
Voltage-gated sodium channels are present in the membrane of most excitable cells and comprise of one pore-forming α subunit which may be associated with either one or two β subunits. The family of sodium channels has nine known members named Nav1.1 through Nav1.9 with the majority being found primarily in the central nervous system, peripheral neurons and dorsal root ganglia. In addition, some sodium channels are found in cardiac myocytes (primarily Nav1.5) while Nav1.4 is located in skeletal muscle.
SB Drug Discovery offers a comprehensive panel of sodium channel assays for HTS, lead optimization studies and selectivity profiling. Our assays have been validated by experienced in-house electrophysiologists using rigorously optimized SOPs to ensure data of the highest quality and consistency.
To discuss your next ion channel project or to receive a quote, visit our contact page or call +44 141 587 6100.