Potassium Channel Assays

K2P2.1 (TREK-1) Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

K2P2.1 - Fluorescence Assay

TREK-1 assay

Figure 1: Dose response curve for agonist BL 1249 against K2P2.1. EC50 value 22.6μM.

K2P2.1 - Fluorescence Assay

TREK-1 assay

Figure 2: Dose response curve for antagonist Fluoxetine against K2P2.1. IC50 value 65µM.


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