TRP channel assays

TRP Channel Screening & Selectivity Panels

TRP Channels

Transient receptor potential channels (TRP channels) are a group of more than 30 ion channels and can be sub-divided into 6 families: TRPC (canonical), TRPA (ankyrin), TRPV (vanilloid), TRPM (melastatin), TRPP (polycystic) and TRPML (mucolipin). TRP channels are found throughout the body and mediate a variety of sensations including pain, extreme temperatures, taste and vision and are activated by a broad range of molecules including allicin, capsaicin and menthol.

SB Drug Discovery offers the largest selection of commercially available TRP channel assays, spanning HTS, lead optimization studies and TRP channel selectivity profiling. Our TRP assays have been validated by experienced in-house electrophysiologists using rigorously optimized SOPs to ensure data of the highest quality and consistency.

To discuss your next ion channel project or to receive a quote, visit our contact page or call +44 141 587 6100.

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TRPA assays

Channel Species Fluorescence Assay Electrophysiology Assay
TRPA1 Human Green Dot Green Dot
TRPA1 Mouse Green Dot Green Dot
TRPA1 Rat Green Dot Green Dot
TRPA1 Monkey Green Dot Green Dot
TRPA1 Guinea Pig Green Dot Green Dot
TRPA1 Sheep Green Dot Green Dot
TRPA1 Dog Green Dot Green Dot

TRPC assays

Channel Species Fluorescence Assay Electrophysiology Assay
TRPC1 Human Green Dot Green Dot
TRPC3 Human Green Dot Green Dot
TRPC4 Human Green Dot Green Dot
TRPC5 Human Green Dot Green Dot
TRPC5/M2 Human Green Dot Green Dot
TRPC5 Mouse Green Dot Green Dot
TRPC5 Rat Green Dot Green Dot
TRPC6 Human Green Dot Green Dot
TRPC6 Mouse Green Dot Green Dot
TRPC6 Rat Green Dot Green Dot
TRPC7 Human Green Dot Green Dot

TRPM assays

Channel Species Fluorescence Assay Electrophysiology Assay
TRPM2 Human Green Dot Green Dot
TRPM3 Human Green Dot Green Dot
TRPM4 Human Green Dot Green Dot
TRPM5 Human Green Dot Green Dot
TRPM5 Mouse Green Dot Green Dot
TRPM8 Human Green Dot Green Dot

TRPML assays

Channel Species Fluorescence Assay Electrophysiology Assay
TRPML1 Human Green Dot Green Dot
TRPML2 Human Green Dot Green Dot
TRPML3 Human Green Dot Green Dot

TRPV assays

Channel Species Fluorescence Assay Electrophysiology Assay
TRPV1 Human Green Dot Green Dot
TRPV1 Mouse Green Dot Orange Dot
TRPV1 Rat Green Dot Green Dot
TRPV2 Human Green Dot Orange Dot
TRPV2 Mouse Green Dot Green Dot
TRPV2 Rat Green Dot Orange Dot
TRPV3 Human Green Dot Green Dot
TRPV3 Mouse Green Dot Orange Dot
TRPV3 Rat Green Dot Orange Dot
TRPV4 Human Green Dot Green Dot
TRPV4 Mouse Green Dot Orange Dot
TRPV4 Rat Green Dot Orange Dot
TRPV5 Human Green Dot Green Dot
TRPV5 Mouse Green Dot Orange Dot
TRPV5 Rat Green Dot Orange Dot
TRPV6 Human Green Dot Green Dot
TRPV6 Mouse Green Dot Orange Dot
TRPV6 Rat Green Dot Orange Dot