TRP Channels

TRPML1 Screening Assays

Species: Human

Subunits / Accessory Proteins: N/A

Cell Type: HEK-293

Assay Platforms: Fluorescence, Manual Patch Clamp, QPatch

Services: HTS, single concentration / dose response studies, selectivity profiling

TRPML1 - QPatch Assay

TRPML1 assay

Figure 1: Superimposed voltage and current traces showing inward and outward TRPML1 current in the presence of agonist ML-SA1.

TRPML1 - QPatch Assay

TRPML1 assay

Figure 2: Concentration-dependent effect of Lanthanum Chloride on the normalised response obtained from HEK-293 cells stably expressing TRPML1 channels.


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