Case Study

Custom Cell Line Generation for Drug Discovery

Accelerate your research with custom cell-based tools designed by experts.

Sygnature Discovery’s specialist cell biology team has over 20 years of experience developing high-quality, custom recombinant cell lines to support drug discovery across a wide range of target classes – including ion channels, GPCRs, transporters and more.

We offer fully validated, stable monoclonal cell lines to meet the complex demands of modern drug discovery. Our custom solutions help you address challenges such as target expression control, protein localisation, multi-gene expression and vector design, ensuring consistent, scalability and reliable data generation.

From assay-ready cell lines to complex reporter systems, we tailor every element to your target biology and screening needs. We also integrate advanced readouts including electrophysiology, radioligand binding, flow cytometry, cAMP, calcium flux, membrane potential, biosensors and more.

Whether you’re investigating receptor signalling, protein-protein interaction, transporter activities or intracellular trafficking, out custom cell-based tools and scientific insights provide a platform for discovery.

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