Chloride Channels

Introduction CLC-Ka and CLC-Kb are members of the CLC family of chloride channels and transporters, crucial for maintaining chloride ion homeostasis across cell membranes. CLC-Ka is predominantly found in the thin ascending limb of Henle’s loop, while CLC-Kb is...

Electrophysiological Characterization of Functional and Pharmacological Effects of CLC-1 and CLC-2 Channel Activity Introduction The CLC family comprises of voltage-dependent cell surface chloride (Cl-) ion channels and intracellular Cl-/H+ transporters which perform...