Discover how SB Drug Discovery’s innovative cell-based tools, including stable GIP receptor and β-Arrestin cell lines, can advance your drug discovery efforts. By leveraging real-time monitoring of receptor-β-Arrestin interactions, biased signalling studies, and...
CASE STUDIES
GPCR Studies
Comparison of hallucinogenic versus non-hallucinogenic psychedelics on 5HT2A receptors
Unlock new potential in 5HT2A receptor drug discovery with SB Drug Discovery’s advanced cell-based assay suite, meticulously designed to profile and differentiate serotonergic ligands. Leveraging assays that assess calcium mobilization, β-arrestin recruitment, and...
Optimizing GPCR assays with chimeric G proteins
Introduction Cell-based assays represent an important step in understanding the functional effects of GPCR modulation. Having access to high quality cellular tools is critical in driving forward these studies, providing reproducible data and clear insight when you...