Cell Line Generation
Delivering Quality and Performance to your Drug Discovery Research
When it comes to the success of your drug discovery research, reagent quality and performance cannot be compromised. That’s why, at SB, we specialize in delivering premium, custom cell line generation solutions that provide a competitive advantage.
Years of Experience
Cell Lines Generated
Customer Projects
Utilising the latest technologies and innovative approaches, our team of leading scientists meticulously interrogates hundreds of individual cell clones at each stage of the cell line generation process, ensuring the highest quality reagents and target solutions for your research needs. Our extensive cell biology experience has enabled us to streamline our development processes to deliver rapid, cost-effective stable cell lines and assay systems. With over 20 years of experience, SB has the expertise and capabilities to meet your cell line generation needs.
Our Customizable Cell Line Generation Process
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Precision Construct Design
Optimal expression of your target of interest via custom-made expression constructs. -
Antibiotic Selection Optimization
Identifying the optimal selection concentration for your specific cell type. -
Optimized Transfection
Successfully introducing expression constructs into challenging cell types and validating target expression. -
Clonal Isolation
Identifying individual cell clones using limiting dilution and expansion under antibiotic selection. -
Functional Profiling
Thoroughly assessing functional attributes of isolated clones to identify the most fitting candidates. -
Quality Check
Comprehensive quality control criteria, ensuring expression stability and reliability. -
Amplification and Stock Generation
Expansion and preparation of stocks for future applications.
Plasmid
Generation
Functional
Validation
Clone
Characterisation
Functional
Assessment
QC Process &
Stock Generation
Stable Cell
Line Delivery
Our streamlined custom cell line generation process creates reliable and consistent stable cell reagents displaying robust expression of your desired target.
Efficient solutions for your research
ion channels
Our electrophysiology team provide a wealth of expertise to support the generation of recombinant ion channel cell lines. Through precise selection of reagents tailored to your specific ion channel interests, we facilitate the advancement of your ion channel research.
Receptors
Using cutting-edge cell-based assay technologies to study biased signalling, we create robust receptor expressing cell lines to further your research. In addition, our experienced scientists develop optimized assays to investigate downstream signalling pathways.
Specialized Cell Lines
Supplementing our expertise in ion channel and receptor cell line generation, our experience extends to generating recombinant cell lines expressing an array of membrane proteins, cytosolic proteins, and complex reporter systems.
Contact SB Drug Discovery
To learn more about our services or to request a quote.
e-Book
Download our eBook to discover how our expert-driven, custom cell line generation services provide high-quality, validated solutions to accelerate your drug discovery research from target validation to lead optimization.
