Ion Channel Studies
Sodium Channels
Flexible assay formats
Leveraging state-of-the-art high-throughput automated electrophysiology, SB Drug Discovery has developed and optimized robust screening assays for rapid assessment of sodium channel compound activity. Our flexible assays generate reliable, robust data to advance your sodium channel drug discovery campaigns.
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Sodium Channel Electrophysiology
Figure 1: Representative Nav1.1 current traces before (grey line) and during the presence of increasing concentrations of the blocker tetrodotoxin (blue lines). Currents are obtained using a peak pulse protocol from a holding potential of -120mV to a peak of +0mV.
SB Drug Discovery Case Studies
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